Cause & risk of miscarriage
What is the cause?
The cause is often a predisposition disorder that arose during fertilization.
What is the chance of a miscarriage?
About 10 to 15% of all pregnancies end in miscarriage.
The older you are, the greater the chance of a miscarriage:
- for women under 35 years of age the chance is 1 in 10 pregnancies
- for women between the ages of 35 and 40, the chance is 1 in 5-6 pregnancies
- for women between 40 and 45 years old, the chance is 1 in 3 pregnancies
25,000 women have a miscarriage every year
Factors that increase the risk of miscarriage?
The most important are:
- A higher age; The older you are, the greater the chance of a miscarriage
- Unhealthy lifestyle (smoking and being overweight); Women who smoke and who are overweight experience miscarriage slightly more often than women who do not smoke and are not overweight.
Other factors that occur much less often:
- Chromosomes contain the hereditary material that you pass on to your child. Sometimes a chromosome abnormality in one of the partners is the cause of a recurrent miscarriage. Anyone can unknowingly be a 'carrier' of a chromosome abnormality. A chromosome abnormality cannot be treated. The chance that you have a chromosome abnormality is very small.
- Antibodies are important for the defense against diseases. Some people produce the wrong antibodies, which respond to cells in their own body. This increases the risk of thrombosis, a blockage of a blood vessel. If this happens in the placenta, a miscarriage occurs
- Too much homocysteine. Homocysteine is a substance in the blood that everyone has. It is important for metabolism. Some people have too much of it, which may increase the risk of miscarriage.
- If clotting factors are abnormal, the risk of miscarriage is increased. Coagulation abnormalities are quite rare.
- Abnormal shape of uterus. Some women have a different uterus shape. It may be a double uterus or a septum in the uterine cavity. It is not entirely certain whether an abnormal shape increases the risk of miscarriage.